Zika structure mapped for first time

New microscopy images of the virus reveal a bumpy, golf ball‒shaped structure, similar to that of the dengue and West Nile viruses, researchers report March 31 in Science. It’s the first time scientists have gotten a good look at Zika, the infamous virus that has invaded the Americas and stoked fears that it is causing birth defects and a rare autoimmune disease (SN: 4/2/16, p. 26).
Cracking Zika’s structure is like getting the blueprints of an enemy’s base: Now scientists have a better idea of where to attack. “This certainly gives us great hope that we will be able to find a vaccine or antiviral compounds,” says study coauthor Michael Rossmann of Purdue University in West Lafayette, Ind., who’s known for mapping the first structure of a common cold virus in 1985.
Researchers have been racing to solve Zika’s structure, says UCLA microbiologist Hong Zhou. “I was trying to work on the same thing myself.” But the new study’s authors beat everybody. “I was impressed they were able to do it so quickly,” Zhou says.

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